منابع مشابه
Metaphors Break the Rules
However, it is a general feature of metaphors that they violate hard or soft semantic constraints. They can be analyzed by detecting that these constraints have been violated, and describing how. Some of the gap in understanding can be closed simply by having a crisp model of argument types for the predicates that are denoted in text – a violation of those types is evidence for a metaphor. Clos...
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Marsupials and monotremes, the mammals most distantly related to placental mammals, share essentially the same genome but show major variations in chromosome organization and function. Rules established for the mammalian genome by studies of human and mouse do not always apply to these distantly related mammals, and we must make new and more general laws. Some examples are contradictions to our...
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During the past year, genetic studies of picornaviruses, vastly facilitated by the application of infectious picornaviral cDNAs and RNAs, have contributed to our understanding of the function of individual picornavirus polypeptides and to the genetic processes that operate in these small RNA viruses. Especially notable were the demonstrations that the RNA-dependent RNA polymerase may have a fun...
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Of the many types of DNA-damage repair, this review concentrates on the aspects of DNA single- and double-strand break repair. Originally considered to represent separate routes based on distinct enzymatic machineries, it has recently been shown that these pathways converge and are interlinked at a number of points. Poly(ADP-ribose) polymerase-1 (PARP-1) is a central player in this complicated ...
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The vertebrate retina is a distinctly laminar structure. Functionally, the inner plexiform layer, in which bipolar cells synapse onto amacrine and ganglion cells, is subdivided into two sublaminae. Cells that depolarize at light offset ramify in sublamina a; those that depolarize at light onset ramify in sublamina b. The separation of ON and OFF pathways appears to be a fundamental principle of...
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ژورنال
عنوان ژورنال: Nature
سال: 1988
ISSN: 0028-0836,1476-4687
DOI: 10.1038/334292a0